The coMET package is a web-based plotting tool and R-based package to visualize EWAS (epigenome-wide association scan) results in a genomic region of interest. coMET provides a plot of the EWAS association signal and visualisation of the methylation correlation between CpG sites (co-methylation). The coMET package also provides the option to annotate the region using functional genomic information, including both user-defined features and pre-selected features based on such as the Encode project, ENSEMBL, the annotation tracks from UCSC Genome Browser website, the ROADMAP epigenomics project, the Genotype-Tissue Expression (GTEx) project and FANTOM5 project. The plot can be customized with different parameters, such as plot labels, colours, symbols, heatmap colour scheme, significance thresholds, and including reference CpG sites. The software is designed for epigenetic data, but can also be applied to genomic and functional genomic datasets in any species.

If you use coMET to plot figures in your paper, please cite our paper:
Martin, T.C., Yet, I., Tsai, P-C., Bell and J.T. (2015). “coMET: visualisation of regional epigenome-wide association scan results and DNA co-methylation patterns.” BMC Bioinformatics.

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